Simplifying Therapy for XLPDiplomat supports patients throughout treatment.
X-linked lymphoproliferative disease (XLP) affects the immune system, causing it not to work the way it should. It’s a genetic condition that’s carried on the X chromosome. Because males only have one X chromosome, they can get XLP. Females can be carriers of XLP, but they don’t get it themselves.
Most people who have XLP won’t normally have any symptoms. It starts to cause issues when the person also gets infected with Epstein-Barr virus (EBV), a common virus that will affect most people in their lifetimes.
When someone with XLP gets EBV, their body responds by creating far too many immune cells. This can trigger a condition called hemophagocytic lymphohistiocytosis (HLH), which can put patients at risk of getting hepatitis and lymphoma. It can even be fatal.
XLP is very rare. Only about one in every million males has it. Although it’s a genetic condition, it might not be diagnosed until well into childhood.
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What are the symptoms of XLP?
Blood tests for XLP might show it early in life. Otherwise, people who have XLP usually have no symptoms until they’re infected with EBV. This can trigger the HLH reaction.
Once a person has HLH, they might have a fever or skin rash. They can have enlarged lymph nodes and trouble breathing. Some organs, such as the liver or spleen, might be enlarged, and they might have trouble with their kidneys or heart. They are also at increased risk for cancers such as leukemia and lymphoma.
How does Diplomat help people with XLP?
People who have XLP can benefit from immunoglobulin G (IgG), which can help treat EBV before it causes problems.
At Diplomat Specialty Infusion Group, we know that the treatments used to cope with a defective immune system response can seem complex and confusing, even to an experienced patient. That’s why we guide our patients through every step of therapy, giving the entire healthcare team the resources to help patients succeed.
We provide the proper immune globulin or infection-management therapy, seek third-party financial assistance, and answer clinical or personal questions 24/7.
Remember: The information here — and on linked sites — is not meant to replace advice, care, or a diagnosis from your physician. If you have questions about your condition, please ask your provider.
The information contained herein may not be construed as medical advice. It is for educational purposes only. Diplomat Pharmacy Inc. takes no responsibility for the accuracy or validity of the information contained herein, nor the claims or statements of any manufacturer.
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