Diplomat Specialty Pharmacy® and Diplomat Specialty Infusion Group® are joining the Optum® family.

To learn more about what this means for you, visit our FAQ pages:

Specialty Pharmacy FAQ  •  Infusion Pharmacy FAQ

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Simplifying Therapy for MPS II

Diplomat Specialty Infusion Group supports patients throughout treatment.

MPS II, also called Hunter Syndrome, is an inherited disorder caused by low or absent levels of an enzyme called iduronate 2-sulfatase. Without enough of this enzyme, the body is unable to break down certain sugar molecules in the body, called glycosaminoglycans (GAGs). This causes GAGs to build to toxic levels in cells throughout the body, keeping various organ systems from functioning and developing normally. This can include bones, joints, brain, spinal cord, heart, spleen, or liver.


MPS II occurs almost exclusively in males — approximately one in 100,000 to one in 170,000. It is a progressively debilitating disorder; however, the rate of progression varies among affected individuals.


MPS II is generally divided into two forms: non-neuronopathic and neuronopathic. The non-neuronopathic form usually results in limited or no intellectual impairment. In the neuronopathic form, intellectual impairment may be seen in early childhood. Physical symptoms affecting organs and tissue are similar in both forms of the condition, though sometimes at a reduced severity in the non-neuronopathic form.


GAGs were originally called mucopolysaccharides, which is where this condition gets its name.


For drug information, click here.

Prescriber? Find enrollment forms here.

How can Diplomat help me?

We’ll answer your questions about Diplomat Specialty Infusion Group.


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Upcoming Treatments

We keep you informed about new specialty medications.

Diplomat actively monitors specialty medications in the government's review and approval process. You can search our database to see if there will be new treatment options for your condition you can discuss with your doctor.

Search Our Database.

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Financial Assistance

We’ll look for ways to help you afford therapy.

There are many ways to get help paying for specialty medications. We'll seek third-party programs and support the application process from start to finish.

Learn More

Meet our patients.

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When therapy was approved to treat Jodie’s hypokalemic periodic paralysis, Diplomat was there to help.

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After being diagnosed with multiple sclerosis, Bethany retired. Diplomat helped her adjust to a new normal.

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After living with Crohn's disease for 18 years, Dave needed nutritional support. Diplomat helped him thrive.

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Jacque thought she’d live with hepatitis C forever. But with Diplomat’s help and expertise, she found a cure.

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