Diplomat Specialty Pharmacy® and Diplomat Specialty Infusion Group® are joining the Optum® family.

To learn more about what this means for you, visit our FAQ pages:

Specialty Pharmacy FAQ  •  Infusion Pharmacy FAQ

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Simplifying Therapy for MPS I

Diplomat Specialty Infusion Group supports patients throughout treatment.

MPS I is an inherited disorder caused by low or absent levels of an enzyme called alpha-L-iduronidase. Without enough of this enzyme, the body is unable to break down certain sugar molecules in the body, called glycosaminoglycans (GAGs). This causes GAGs to build to toxic levels in cells throughout the body, keeping various organ systems from functioning and developing normally. This can include bones, joints, brain, spinal cord, heart, spleen, or liver.


MPS I used to be divided into three separate syndromes: Hurler syndrome (MPS I-H), Hurler-Scheie syndrome (MPS I-H/S), and Scheie syndrome (MPS I-S), listed from most to least severe. Because there is so much overlap between each of these three syndromes, MPS I is currently divided into two types: severe and attenuated (reduced severity).


  • Symptoms of severe MPS I generally present within the first six to twelve months after birth.
  • Individuals with attenuated MPS I have milder features that may not present until later in childhood.


Severe MPS I occurs in approximately one in 100,000 newborns. Attenuated MPS I is less common and occurs in about one in 500,000 newborns.


GAGs were originally called mucopolysaccharides, which is where this condition gets its name.


For drug information, click here.

Prescriber? Find enrollment forms here.

How can Diplomat help me?

We’ll answer your questions about Diplomat Specialty Infusion Group.


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Upcoming Treatments

We keep you informed about new specialty medications.

Diplomat actively monitors specialty medications in the government's review and approval process. You can search our database to see if there will be new treatment options for your condition you can discuss with your doctor.

Search Our Database.

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Financial Assistance

We’ll look for ways to help you afford therapy.

There are many ways to get help paying for specialty medications. We'll seek third-party programs and support the application process from start to finish.

Learn More

Meet our patients.

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When therapy was approved to treat Jodie’s hypokalemic periodic paralysis, Diplomat was there to help.

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After being diagnosed with multiple sclerosis, Bethany retired. Diplomat helped her adjust to a new normal.

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After living with Crohn's disease for 18 years, Dave needed nutritional support. Diplomat helped him thrive.

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Jacque thought she’d live with hepatitis C forever. But with Diplomat’s help and expertise, she found a cure.

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